La maladie de Parkinson au Canada (serveur d'exploration)

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Stop-related subthalamic beta activity indexes global motor suppression in Parkinson's disease.

Identifieur interne : 000197 ( Main/Exploration ); précédent : 000196; suivant : 000198

Stop-related subthalamic beta activity indexes global motor suppression in Parkinson's disease.

Auteurs : Jan R. Wessel [États-Unis] ; Ayda Ghahremani [Canada] ; Kaviraja Udupa [Canada] ; Utpal Saha [Canada] ; Suneil K. Kalia [Canada] ; Mojgan Hodaie [Canada] ; Andres M. Lozano [Canada] ; Adam R. Aron [États-Unis] ; Robert Chen [Canada]

Source :

RBID : pubmed:27474845

Abstract

Rapid action stopping leads to global motor suppression. This is shown by studies using transcranial magnetic stimulation to measure corticospinal excitability of task-unrelated effectors (e.g., from the hand during speech stopping). We hypothesize that this global suppression relates to the STN of the basal ganglia. Several STN local field potential studies in PD patients have shown increased ß-band power during successful stopping.

DOI: 10.1002/mds.26732
PubMed: 27474845


Affiliations:


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